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The Straight Dope: Does Tylenol + alcohol = liver failure?:
The real problem with drugs like Tylenol is that the difference between a therapeutic (that is, medically effective) dose and a toxic one is surprisingly small. In adults the maximum safe dosage is four grams (eight 500-milligram tablets) over a 24-hour period. The toxic dose is a mere seven grams taken all at once.Edit: removed the 2nd part of the article title, because we all know it's a trick question; socialist Canada cannot afford buildings. ;-P